单纯收缩期高血压的治疗是高血压治疗领域中的一个主要问题，在DBP低于60mmHg而SBP远远高于目标水平的患者中，尤其是在合并冠心病的患者中，我们应该如何处理？您推荐哪种药物联合方案？
The treatment of isolated systolic hypertension is a major problem in the field of hypertension therapy， in patients with DBP less than 60mmHg but SBP far above the standard， especially in whom accompanied with coronary artery disease， how can we do? Which therapeutic combination do you prefer to?