<International Circulation>: And recently there have been many advances in ablation of renal nerves……

　　《国际循环》：肾交感神经射频消融术最近取得了很多的进展。
　　Dr Konstam: Now that is a very promising therapy for hypertension with trials going on right now. The preliminary results are extremely encouraging in patients with pharmacologically unmanageable hypertension. The early trials show that these patients do much better. This could be a blockbuster therapy for hypertension. There is also， independent of hypertension， a significant interest in the utility of that intervention in heart failure patients because of the role of excessive sympathetic adrenergic activity in the heart failure patient. The renal sympathetic nerves which travel along the renal arteries are both afferent and efferent， impacting the adrenergic innervations of the kidneys as well as impacting on systemic sympathetic tone. Therein lies a lot of the rationale for potentially migrating that therapy to use in heart failure. There is a lot of interest in clinical investigation in that area. Discussions are certainly underway to begin trials， but there are no results available as such.

肾交感神经射频消融术在心力衰竭治疗中的应用前景