<International Circulation>: The use of beta blockers appears to increase the risk of diabetes, but it can also reduce the risk of cardiovascular events. So what is the role of beta blockers in hypertensive therapy?
《国际循环》:能否为我们介绍下哪些患者适合应用CCB?
Myra Klienpeter:在ACCORD试验的强化降压组,更多患者应用了CCB。对于单纯收缩期高血压患者,我倾向于更多应用CCB。目前上市的单片复方制剂中,有很多含有长效CCB氨氯地平,应用这种单片复方制剂的患者能够较快地将血压降下来,有助于血压达标。
<International Circulation>: Could you extend this on what patients you would prefer to use calcium channel blockers for?
Dr Myra Klienpeter: In the intensive therapy of the ACCORD trial there was more calcium channel blocker usage. In those patients with isolated systolic hypertension I tend to use more calcium channel blockers. A lot of the combination medication being brought into the market in which long standing calcium channel blocker amlodipine is added to the drug and those patients are able to achieve a low blood pressure in a relatively rapid fashion and help them reach their blood pressure goals.