<International Circulation>: As president of this year’s EAS congress what were the major developments in terms of advancing our understanding and improving the management of atherosclerosis?
    Prof. Beisiegel:  In terms of advancing our understanding of this condition I would like to highlight the latest findings from the Global Genomewide Association Analysis of Coronary Artery Disease; which were presented by Professor Heribert Schunkert who coordinates this group. Under the name CARDIoGRAM the group revealed more than 20 highly reproducible genetic loci which are connected to myocardial infarction and coronary artery disease. This certainly is a very intriguing area and we look forward in anticipation from further findings which could help us understand more clearly the pathophysiological mechanisms involved as well as help us screen the population for the elevated risk of developing atherosclerosis. 2. Another important development from this year’s meeting was that the EAS Consensus Panel agreed on a new recommendation concerning lipoprotein-a. For a long time we have known that lipoprotein-a is a risk factor for the development of cardiovascular disease (CVD)，but were unsure as to whether we should measure it or not. The panel which comprises 18 renowned international experts in atherosclerosis and CVD all recommended that lipoprotein-a should be taken into account when screening patients for their risk of CVD. 3. Based from published experiments from last year; there was also considerable interest on the revealing properties of brown adipose tissue in reducing the risk of CVD. Unpublished data found that increasing the activity of brown adipose tissue in mouse models lead to the abolishment of high levels of triglycerides during the postprandial phase. The brown adipose tissue can act like a sink for triglycerides and this might be a very interesting new system in turning the screw in order to decrease triglycerides by increasing the activity of brown adipose tissue. Normally we stimulate brown adipose tissue by cold， and if you put the mice in cold environments， triglycerides go down and they go into the brown adipose tissue. This effect might be mimicked in future by suitable synthetic molecules. 4. Last but not least there was an outstanding presentation by Professor Johan Auwerx who shared some new data on resveratrol. This is a component of red wine and has a number of beneficial effects which includes aiding in the burning of excess energy.
    在促进对动脉粥样硬化的了解方面，冠心病的全球全基因组关联分析的最新研究——CARDIoGRAM，发现了20多个与心肌梗死和冠心病相关的具有高度重复性的基因位点。该研究有助于更清楚地了解动脉粥样硬化的病理生理机制及筛查动脉粥样硬化高危人群。
    本次大会公布了关于脂蛋白a的专家共识。EAS共识专家组由动脉粥样硬化和心血管疾病领域的18位国际知名专家组成，他们一致推荐在筛查患者的心血管风险时应考虑脂蛋白a水平。
    基于去年发表的试验数据，显示出观察褐色脂肪组织的特点以减少心血管风险方面的研究兴趣。未发表的数据显示，在小鼠模型增加褐色脂肪组织的活性能够预防餐后甘油三酯的升高。褐色脂肪组织能够储存甘油三酯，通过增加褐色脂肪组织的活性来降低甘油三酯可能是一个非常有意义的新方法。通常以低温来刺激褐色脂肪组织，如果将小鼠放入低温环境中，甘油三酯水平将下降，进入褐色脂肪组织。
    Johan Auwerx教授介绍了有关白藜芦醇的研究。白藜芦醇是红酒的成分之一，具有一系列有益作用，包括有助于消耗多余能量。